down

Definitions
Examples

(noun): A negative aspect; a downer.
(noun): A grudge (on someone).
(noun): An act of swallowing an entire drink at once.
(noun): A single play, from the time the ball is snapped (the start) to the time the whistle is blown (the end) when the ball is down, or is downed.
(noun): (crosswords) A clue whose solution runs vertically in the grid.
(noun): A downstairs room of a two-story house.
(noun): Down payment.
(verb): To knock (someone or something) down; to cause to come down, to fell.
(verb): To lower; to put (something) down.
(verb): To defeat; to overpower.
(verb): To disparage, to put down.
(verb): To go or come down; to descend.
(verb): To drink or swallow, especially without stopping before the vessel containing the liquid is empty.
(verb): To render (the ball) dead, typically by touching the ground while in possession.
(verb): (pocket billiards) To sink (a ball) into a hole or pocket.
(adjective): Sad, unhappy, depressed, feeling low.
(adjective): (normally in the combination 'down with') Sick or ill.
(adjective): At a lower level than before.
(adjective): Having a lower score than an opponent.
(adjective): (following the noun modified) Out.
(adjective): (with "on") Negative about, hostile to.
(adjective): Comfortable with, accepting of, approachable.
(adjective): Inoperable; out of order; out of service.
(adjective): Finished (of a task); defeated or dealt with (of an opponent or obstacle); elapsed (of time). Often coupled with to go (remaining).
(adjective): (police, of a person) Wounded and unable to move normally, or killed.
(adjective): (of an aircraft) Mechanically failed, collided, shot down, or otherwise suddenly unable to fly.
(adjective): Thoroughly practiced, learned or memorised; mastered. (Compare down pat.)
(adjective): Downright; absolute; positive.
(adjective): Accepted or respected, especially in the black or thug community.
(adjective): Facing downwards.
(adverb): From a higher position to a lower one; downwards.
(adverb): At a lower or further place or position along a set path.
(adverb): South (as south is at the bottom of typical maps).
(adverb): Away from the city (regardless of direction).
(adverb): At or towards any place that is visualised as 'down' by virtue of local features or local convention, or arbitrarily, irrespective of direction or elevation change.
(adverb): Towards the opponent's side (in ball-sports).
(adverb): Into a state of non-operation.
(adverb): To a subordinate or less prestigious position or rank.
(adverb): In the direction leading away from the principal terminus, away from milepost zero.
(adverb): (sentence substitute) Get down.
(adverb): (academia) Away from Oxford or Cambridge.
(adverb): From a remoter or higher antiquity.
(adverb): So as to lessen quantity, level or intensity.
(adverb): So as to reduce size, weight or volume.
(adverb): From less to greater detail.
(adverb): So as to secure or compress something to the floor, ground, or other (usually horizontal) surface.
(adverb): (intensifier) Used with verbs to add emphasis to the action of the verb.
(adverb): Used with verbs to indicate that the action of the verb was carried to some state of completion, rather than being of indefinite duration.
(preposition): From the higher end to the lower of.
(preposition): From nouth to south of.
(preposition): From one end to another of (in any direction); along.
(preposition): At (a given place that is seen as removed from one's present location or other point of reference).

I love almost everything about my job. The only down is that I can't take Saturdays off.
I bet after the third down, the kicker will replace the quarterback on the field.
I haven't solved 12 or 13 across, but I've got most of the downs.
She lives in a two-up two-down.
A single rifle shot downed the mighty beast.