vexed

Definitions
Examples

(verb): To trouble aggressively, to harass.
(verb): To annoy, irritate.
(verb): To cause (mental) suffering to; to distress.
(verb): To twist, to weave.
(verb): To be irritated; to fret.
(verb): To toss back and forth; to agitate; to disquiet.
(adjective): Annoyed, irritated or distressed
(adjective): Much debated, discussed or disputed

She became more and more vexed as she struggled to cope with the demands of the job.